Sharingan Users Star in New Naruto Shippuden Eye-Drops Collab

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Naruto Shippuden has partnered with Japan’s Rohto Pharmaceutical for a dynamic new collaboration involving the company’s popular “Rohto Z!” series of eye drops.

This campaign focuses specifically on the “Sharingan,” the powerful ocular ability that serves as a central plot point throughout the series history.

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Naruto Shippuden, the celebrated sequel to the original Naruto anime, adapts Masashi Kishimoto’s manga and follows the teenage ninja Naruto Uzumaki as he defends his village from the criminal organization Akatsuki.

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Much of the series’ conflict revolves around the Uchiha clan and their hereditary “Dojustu” (eye technique) known as the Sharingan, which grants the user enhanced perception, the ability to copy jutsu, and the power to cast illusions.

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For this collaboration, Rohto has selected three of the most iconic Sharingan users in the franchise’s history to represent different formulations of their eye care products.

The lineup features Sasuke Uchiha, the avenger seeking power to restore his clan; Itachi Uchiha, Sasuke’s prodigal older brother; and Kakashi Hatake, the legendary “Copy Ninja” and mentor to Team 7.

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Each bottle features a different color scheme and design corresponding to the character and their specific eye technique.

The full collaboration lineup includes:

  • Rohto Z! b NARUTO (Sasuke Uchiha Model)
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Designed for “eyes fighting fatigue,” this formula features a blue bottle design. 

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It contains L-potassium aspartate to promote cell respiration and Vitamin B6 to boost metabolism, along with ingredients to reduce redness and itching. The cooling level is rated at 8.

  • Rohto Z! Contact b NARUTO (Kakashi Hatake Model)
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Designed for “eyes fighting dryness with contacts,” this green bottle formula boasts the highest cooling level in Rohto’s lineup (Level 8+). 

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It contains “W minerals” (Potassium chloride and Sodium chloride) and Hypromellose to retain moisture, making it suitable for use with naked eyes or while wearing any type of contact lens.

  • Rohto Z! Pro d NARUTO (Itachi Uchiha Model) 
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Designed for “eyes fighting the fatigue of overwork,” this red bottle represents the premium option in the range.

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It features a “maximum grade” cooling level of 8+ and contains Neostigmine methylsulfate to improve focus adjustment, Vitamin B6, and Chondroitin sulfate sodium to protect the cornea.

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The “Naruto x Rohto Z!” collaboration bottles are scheduled to go on sale starting Thursday, January 29, 2026.

They will be available at drugstores and retailers nationwide across Japan.

This post may contain affiliate links, and Essential Japan may earn a commission if you purchase through them.

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